Classification-Biased Apparent Brain Age for the Prediction of Alzheimer's Disease

نویسندگان

چکیده

Machine Learning methods are often adopted to infer useful biomarkers for the early diagnosis of many neurodegenerative diseases and, in general, neuroanatomical ageing. Some these estimate subject age from morphological brain data, which is then indicated as “brain age”. The difference between such a predicted and actual chronological can be used an indication pathological deviation normal An important use model biomarker prediction Alzheimer's disease (AD) structural Magnetic Resonance Imaging (MRI). Many different machine learning approaches have been applied this specific predictive task, some achieved high accuracy at expense descriptiveness model. This work investigates appropriate combination data science techniques linear models provide, same time, good descriptiveness. proposed method based on workflow that include typical methods, outliers detection, feature selection, regression, logistic regression. In particular, novel inductive bias introduced regression model, aimed improving specificity classification task. compared other AD with without age, including Support Vector Machines Deep Neural Networks. study adopts MRI scans 1, 901 subjects acquired three repositories (ADNI, AIBL, IXI). A only apparent has 88% 92%, respectively, male female subjects, repeated cross-validation analysis, thus achieving comparable or superior performance than state art methods. advantage it maintains semantics input space throughout tasks. accurate also highly descriptive generate potentially insights predictions.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

the innovation of a statistical model to estimate dependable rainfall (dr) and develop it for determination and classification of drought and wet years of iran

آب حاصل از بارش منبع تأمین نیازهای بی شمار جانداران به ویژه انسان است و هرگونه کاهش در کم و کیف آن مستقیماً حیات موجودات زنده را تحت تأثیر منفی قرار می دهد. نوسان سال به سال بارش از ویژگی های اساسی و بسیار مهم بارش های سالانه ایران محسوب می شود که آثار زیان بار آن در تمام عرصه های اقتصادی، اجتماعی و حتی سیاسی- امنیتی به نحوی منعکس می شود. چون میزان آب ناشی از بارش یکی از مولفه های اصلی برنامه ...

15 صفحه اول

the role of type-d personality, social support and self-compassion in prediction of health behaviors in coronary heart disease patients

نظر به اهمیت و تاثیر روزافزون عوامل روانی – اجتماعی در سلامت جسمی و تاثیر عوامل روان شناختی در بروز بیماریهای مختلف از جمله بیماریهای قلبی و عروقی این پژوهش با هدف کلی بررسی ارتباط تیپ شخصیتی d ، حمایت اجتماعی و خود دلسوزی در پیش بینی رفتارهای بهداشتی بیماران کرونر قلبی و تعیین تفاوت بین بیماران کرونر قلبی با و بدون جراحی و افراد سالم در این متغیرها و رفتارهای بهداشتی آنان، انجام گرفت. جامعه آ...

15 صفحه اول

Regional Analysis of FDG-PET for the Classification of Alzheimers Disease

We present a multi-region analysis of FDG-PET data for classification of subjects from the Alzheimer’s Disease Neuroimaging Initiative. Image data were obtained from 69 healthy controls, 71 Alzheimer’s disease patients, and 147 patients with mild cognitive impairment. Anatomical segmentations were automatically generated in the native MRI space of each subject, and regional signal intensities e...

متن کامل

study of cohesive devices in the textbook of english for the students of apsychology by rastegarpour

this study investigates the cohesive devices used in the textbook of english for the students of psychology. the research questions and hypotheses in the present study are based on what frequency and distribution of grammatical and lexical cohesive devices are. then, to answer the questions all grammatical and lexical cohesive devices in reading comprehension passages from 6 units of 21units th...

the use of appropriate madm model for ranking the vendors of mci equipments using fuzzy approach

abstract nowadays, the science of decision making has been paid to more attention due to the complexity of the problems of suppliers selection. as known, one of the efficient tools in economic and human resources development is the extension of communication networks in developing countries. so, the proper selection of suppliers of tc equipments is of concern very much. in this study, a ...

15 صفحه اول

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Frontiers in Neuroscience

سال: 2021

ISSN: ['1662-453X', '1662-4548']

DOI: https://doi.org/10.3389/fnins.2021.673120